Publications

*             *Corresponding Author

񤭦~Zפ]2010~^G

1.          Hui-Ling Liao, Tso-Chiang Ma, Yi-Chun Li, Jin-Tang Chen, Yuan-Shiun Chang*: Concurrent Use of Corticosteroids with Liquorice Containing TCM Preparations in Taiwan: A National Health Insurance Database Study. Journal of Alternative and Complementary Medicine, 16(5): 539-544, 2010.

2.          Shang-Chih Lai, Yu-Ling Ho, Shun-Chieh Huang, Tai-Hung Huang, Zhen-Rung Lai, Chi-Rei Wu, Kuo-Yuan Lian, Yuan-Shiun Chang*: Antioxidant and Antiproliferative Activities of Desmodium triflorum (L.) DC. The American Journal of Chinese Medicine, 38(2): 329-342, 2010.

3.          Wen-Neng Lin, Hsiu-Ying Lu, Meng-Shiou Lee, Shih-Ying Yang, Hsi-Jien Chen, Yuan-Shiun Chang, Wen-Te Chang. Evaluation of the cultivation age of dried Ginseng radix and Its commercial products by using 1H-NMR fingerprint analysis. American Journal of Chinese Medicine, 38(1): 205-218, 2010.

4.          Zhen-Rung Lai, Wen-Huang Peng, Yu-Ling Ho, Shun-Chueh Huang, Tai-Hung Huang, Shang-Chih Lai, Yoe-Ray Ku, Jen-Chieh Tsai, Ching-Ying Wang, Yuan-Shiun Chang*: Analgesic and Anti-inflammatory Activities of the Methanol Extract of Kalanchoe gracilis (L.) DC Stem in Mice. The American Journal of Chinese Medicine, 38(3): 529-546, 2010.

5.          @lBɹaB*GTثCӪܮƬʵAs;dz6: 19-30A2010C

6.          Po-Chow Hsieh, Guan-Jhong Huang, Yu-Ling Ho, Yaw-Huei Lin, Shyh-Shyun Huang, Ying-Chen Chiang, Mu-Chuan Tseng and Yuan-Shiun Chang*: Activities of antioxidants, \-Glucosidase inhibitors and aldose reductase inhibitors of the aqueous extracts of four Flemingia species in Taiwan. Botanical Studies, 51: 293-302, 2010.

7.          Kuan-Hung Lu, Yuh-Fang Chang, Pen-Hui Yin, Ting-Ting Chen, Yu-Ling Ho, Yuan-Shiun Chang*, and Chin-Wen Chi: Anti-leukemia effect of Mucuna macrocarpa stem extract by inducing apoptosis in HL-60, human leukemia cells. Integrative Cancer Therapies, 9(3):298-308, 2010.

8.          Guan-jhong Huang, Chih-Min Yang, Yuan Shiun Chang, Sakae Amagaya, Hsiao-Chieh Wang, Wen-Chi Hou, Shyh-Shyun Huang, Miao-Lin Hu*: Hispolon Suppresses SK-Hep1 Human Hepatoma Cell Metastasis by Inhibiting Matrix Metalloproteinase-2/9 and Urokinase-Plasminogen Activator through the PI3K/Akt and ERK Signaling PathwaysAJournal of Agricultural and Food Chemistry, 58:9468-9475, 2010.

9.          Ying-Chen Chiang, Guan-Jhong Huang, Yu-Ling Ho, Po-Chow Hsieh, Hsiao-Ping Chung, Fong-In Chou, Yuan-Shiun Chang: Influence of gamma irradiation on microbial load and antioxidative characteristics of Polygoni Multiflori Radix. Process Biochemistry, 46: 777-782, 2011.

10.      Po-Chou Hsieh, Yu Ling, Ho, Huang Guan-jhong, Ming-Hsing Huang, Ying-Chen Chiang, Shyh-Shyun Huang, Wen-Chi Hou, Yuan Shiun Chang*: Hepatoprotective effect of the aqueous extract of Flemingia macrophyll on carbon tetrachloride-induced acute hepatotoxicity in rats through anti-oxidative activities. The American Journal of Chinese Medicine, 39(2): 349-365, 2011.

11.      Tien-Ning Chang, Yu-Ling Ho, Guan-Jhong Huang, Shyh-Shyun Huang, Chao-Jung Chen, Po-Chou Hsieh, Ying-Chen Chiang and Yuan-Shiun Chang*: Hepatoprotective Effect of Crossostephium chinensis (L.) Makino in Rats. The American Journal of Chinese Medicine, 39(3): 503-521, 2011.

12.      Ying-Chen Chiang, Wen-Te Chang, Mann-Duan Chen, Guan-Hua Lai, Hsi-Jien Chen, Jung Chao, Ming-Kuem Lin, Yuan Shiun Chang, Yu-Mei Chou, Meng-Shiunn Lee and Meng-Shiou Lee*: Rapid identification of the medicinal plant Taraxacum formosanum and distinguishing of this plant from its adulterants by ribisomal DNA internal transcribed spacer (ITS) based DNA barcode. African Journal of Biotechnology, 10(24):4838-4843, 2011.

13.      Tien Ning Chang, Shyh-Shyun Huang, Yuan Shiun Chang, Chi-I Chang, Hsin ling Yang, Jeng Shyan Deng, Yueh-Hsiung Kuo, Guan Jhong Huang: Analgesic Effects and the Mechanisms of Anti-inflammation of Taraxeren-3-one from Diospyros maritima in Mice. Journal of Agricultural and Food Chemistry, 59(17): 9112-9119, 2011.

14.      Zhen-Rung Lai, Yu-Ling Ho, Shun-Chieh Huang, Tai-Hung Huang, Shang-Chih Lai, Jen-Chieh Tsai, Ching-Ying Wang, Guan-jhong Huang, Yuan-Shiun Chang*: Antioxidant, Anti-inflammatory, and Antiproliferative Activities of Kalanchoe gracilis (L.) DC Stem. American Journal of Chinese Medicine, 39(6): 1275-1290, 2011.

15.      Chia Ju Chang, Thing-Fong Tzeng, Shorong-Shii Liou, Yuan Shiun Chang* and I-Min Liu*: Kaempferol Regulates the Lipid-Profile in High-Fat-Diet Fed Rats through an Increase in Hepatic PPAR\ Levels. Planta Medica, 77: 1876-1882, 2011.

16.      Mei Chou Lai, I-Min Liu, Shorong-Shii Liou and Yuan Shiun Chang*: Mesaconitine, One of the Aconitine-type Alkaloids, Plays the Major Role in the Antinociceptive and Anti-inflammatory Activities of Radix Aconiti Carmichaeli (Chuan Wu), Journal of Food and Drug Analysis, 19(3): 362-368, 2011.

17.      Kuan-Hung Lu, Hui-Ju Lee, Min-Li Huang, Shang-Chih Lai, Yu Ling, Ho, Chin-Wen Chi* and Yuan-Shiun Chang*: Enhancement of Arsenic Trioxide-Induced Apoptosis by Mucuna macrocarpa Stem Extract in Human Leukemic Cells via a Reactive Oxygen Species-Dependent Mechanism. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2012/921430, 2012.

18.      Mei Chou Lai, I-Min Liu, Shorong-Shii Liou and Yuan Shiun Chang*: Radix Aconiti Kusnezoffii Exhibits an Antinociceptive Activity Involvement at Central and Peripheral Nervous System. Journal of Food and Drug Analysis, 2(20):501-509, 2012.

19.      Chia Ju Chang, Thing-Fong Tzeng, Shorong-Shii Liou, Yuan-Shiun Chang* and I-Min Liu *: Myricetin Increases Hepatic Peroxisome Proliferator-Activated Receptor \ Protein Expression and Decreases Plasma Lipids and Adiposity in Rats, Evidence-Based Complementary and Alternative Medicine, (2012):787152-787152, 2012.

20.      Tai-Ping Fan*, Greer Deal, Hoi-Lun Koo, Daryl Rees, He Sun, Shaw Chen, Jin-Hui Dou, Valery G. Makarov, Olga N. Pozharitskaya, Alexander N. Shikov, Yeong Shik Kim, Yi-Tsau Huang, Yuan Shiun Chang, William Jia, Alberto Dias, Vivian Chi-woon Wong, Kelvin Chan*: Future development of global regulations of Chinese herbal products, Journal of Ethnopharmacology, (140):568-586, 2012.

21.      Chi-Ren Liao, Yuan Shiun Chang, Wen-Huang Peng, Shang-Chih Lai, Yu Ling, Ho*: Analgesic and Anti-inflammatory Activity of methanol extract of Elaeagnus ldhamii Maxim. in Mice, American Journal of Chinese Medicine, 3(40):581-597, 2012.

22.      Ching-Ying Wang, Shun Chieh Huang, Yongjun Zhang, Lai Zhen Rung, Szu-Hao Kung, Yuan Shiun Chang*, Lin Cheng Wen*: Antiviral ability of Kalanchoe gracilis leaf extract against enterovirus 71 and coxsackievirus A16, Evidence-based Complementary and Alternative Medicine, (2012):503165-503165, 2012.

23.      Yu Ling, Ho, Kun-Cheng Li, Wei Chao, Yuan Shiun Chang*, Huang Guan-jhong*: Korean Red Ginseng Suppresses Metastasis of Human Hepatoma SK-Hep1 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen Activator, Evidence-based Complementary and Alternative Medicine, (2012):965846-965846, 2012.

24.      Yu Ling, Ho, Shyh-Shyun Huang, Jeng-Shyan Deng, Yaw-Huei Lin, Yuan Shiun Chang, Huang Guan-jhong*: In vitro antioxidant properties and total phenolic contents of wetland medicinal plants in Taiwan, Botanical Studies, (53):55-66, 2012.

25.      Chia Ju Chang, Thing-Fong Tzeng, Yuan Shiun Chang*, I-Min Liu*: Beneficial Impact of Zingiber zerumbet on Insulin Sensitivity in Fructose-Fed Rats, Planta Medica, (78):317-325, 2012.

26.      Chia Ju Chang, Thing-Fong Tzeng, Shorong-Shii Liou, Yuan Shiun Chang*, I-Min Liu*: Regulation of lipid disorders by ethanol extracts from Zingiber zerumbet in high-fat diet-induced rats, Food Chemistry, (132):460-467, 2012.

27.      Chia Ju Chang, Thing-Fong Tzeng, Shorong-Shii Liou, Yuan Shiun Chang*, I-Min Liu*: Absence of genotoxic and mutagenic effects of Zingiber zerumbet L. Smith Zingiberaceae extract, Evidence-based Complementary and Alternative Medicine, (2012):406296-406296, 2012.

28.      Chia Ju Chang, Thing-Fong Tzeng, Shorong-Shii Liou, Yuan Shiun Chang*, I-Min Liu*: Acute and 28-Day Subchronic Oral Toxicity of an Ethanol Extract of Zingiber zerumbet (L.) Smith in Rodents, Evidence-based Complementary and Alternative Medicine, (2012):608284-608284, 2012.

29.      Bɹa*BGHPLC kPɴwOWkslBksltqCĪRx 33(2): 230-233, 2013C

30.      Yang Zhao, Chun-Pin Kao, Yuan-Shiun Chang*, Yu-Ling Ho: Quality Assessment on Polygoni Multiflori Caulis Using HPLC/UV/MS Combined with Principle Component Analysis, Chemistry Central Journal, 7:106, 2013.

31.      Hour Mann-Jen, Su-Hua Huang, Ching-Yao Chang, Yen-Kuan Lin, Ching-Ying Wang, Yuan Shiun Chang, Lin Cheng Wen*: Baicalein, ethyl acetate and chloroform extracts of Scutellaria baicalensis inhibit the neuraminidase activity of pandemic 2009 H1N1 and seasonal influenza A viruses, Evidence-based Complementary and Alternative Medicine, 2013(2013):750803, 2013.

32.      Ching-Ying Wang, Shun Chieh Huang, Lai Zhen Rung, Yu-Ling Ho, Yu-Jen Jou, Szu-Hao Kung, Yongjun Zhang, Yuan Shiun Chang*, Lin Cheng Wen: Eupafolin and ethyl acetate fraction of Kalanchoe gracilis stem extract show potent antiviral activities against enterovirus 71 and coxsackievirus A16, Evidence-based Complementary and Alternative Medicine, 2013():591354, 2013.

33.      Chi-Ren Liao, Yu-Ling Ho, Huang Guan-Jhong, Chang Syun Yang, Che-Yi Chao, Yuan Shiun Chang*, Yueh-Hsiung Kuo*: One lignanoid compound and four triterpenoid compounds with anti-inflammatory activity from the leaves of Elaeagnus oldhamii Maxim., Molecules, 18:13218-13227, 2013.

34.      Hui-Ling Liao, Yi-Chun Li, Yu-Ling Ho, Chun-Chen Hsu, Yi-Jen Hung, Yuan-Shiun Chang: Prescription of drugs during pregnancy in taiwan: a NHI database study, Formosa Journal of Clinical Pharmacy, 21(2): 37-45, 2013.

35.      Guan-Jhong Huang, Jeng-Shyan Deng, Shyh-Shyun Huang, Sheng-Yang Wang, Yuan-Shiun Chang*, Yueh-Hsiung Kuo*: Bioassay Guided Isolation and Identification of Anti-inflammatory Active Compounds from the Root of Ficus formosana, Journal of Agricultural And Food Chemistry, 61(46):11008-11015, 2013.

36.      Chi-Ren Liao, Yueh-Hsiung Kuo, Yu-Ling Ho, Ching-Ying Wang, Chang-Syun Yang , Cheng-Wen Lin, Yuan-Shiun Chang*: Studies on Cytotoxic Constituents from the Leaves of Elaeagnus oldhamii Maxim. in Non-Small Cell Lung Cancer A549 Cells, Molecules, 19: 9515-9534, 2014.

37.      Der-Shiang Tsai, Yuan-Shiun Chang, Tsai-Chung Li, Wen-Huang Peng*: Prescription pattern of Chinese herbal products for hypertension in Taiwan: A population-based study, Journal of Ethnopharmacology, 155(3):1534-1540, 2014.

38.      Yi-Kung Lin, Yu-Ling Ho, Yang Zhao, Yuan-Shiun Chang: Quality assessment of Fritillariae Thunbergii Bulbus sold in Taiwan markets using a validated HPLC-UV method combined with hierarchical clustering analysis, Journal of Food and Drug Analysis, 22(4); doi:10.1016/j.jfda.2014.06.004, 2014.

39.      Yang Zhao, Chun-Pin Kao, Kun-Chang Wu, Chi-Ren Liao, Yu Ling, Ho*, Yuan Shiun Chang*: Chemical Compositions, Chromatographic Fingerprints and Antioxidant Activities of Andrographis Herba, Molecules, 19(11):18332-18350, 2014.

40.      Hung-Jin Huang, Hsin-Yi Chen, Yuan-Shiun Chang*, Calvin Yu-Chian Chen: Insight into two antioxidants binding to the catalase NADPH binding site from traditional Chinese medicines, RSC Advances, DOI: 10.1039/C4RA14734K, 2014.

41.      Kun-Cheng Li, Yu-Ling Ho, Wen-Tsong Hsieh, Shyh-Shyun Huang, Yuan-Shiun Chang* and Guan-Jhong Huang*: Apigenin-7-Glycoside Prevents LPS-Induced Acute Lung Injury via Downregulation of Oxidative Enzyme Expression and Protein Activation through Inhibition of MAPK Phosphorylation, Int. J. Mol. Sci., 16: 1736-1754, 2015.

42.      Yang Zhao, Yuan-Shiun Chang, Pei Chen: Differentiation of Aurantii Fructus Immaturus from Poniciri Trifoliatae Fructus Immaturus using flow-injection mass spectrometric (FIMS) metabolic fingerprinting method combined with chemometrics, Journal of Pharmaceutical and Biomedical Analysis, 107: 251-257, 2015.

 

~Zפ]~2008^G

1.          B̰QBaGOW¹aBgC쭻PѥPäľǬsAľǰ|~8: 745-819, 1977.

2.          Chang, Y.S., Pezzuto, J.M., Fong, H.H.S., and Farnsworth, N.R.: Evaluation of the mutagenic potential of American ginseng (Panax quinquefolius). Planta Med. 1986: 338-339, 1986.

3.          Swanson S.M., Jiang, J.X., Chang, Y.S., de Souza, N.J., and Pezzuto, J.M.: A rapid and sensitive bioassay involving cultured rat glioma cells to screen for substances capable of elevating intracellular cyclic AMP concentration. J. Nat. Prod. 51: 929-936, 1988.

4.          ӿBۡBTB嶩vBBAGOWaϤ|{pAx1:58-66, 1990.

5.          Hsieh, M.T., Peng, W.H., Yeh, F.C., Tsai, H.Y. and Chang, Y.S.: Studies on the Anticonvulsive, Sedative, and Hypothermic Effects of Periostracum Cicadae. J. Ethanopharmacol. 35: 83-90, 1991.

6.          ©BBzBtBjABjGOWT[RΧܦpOʦsAľǰ|x1(2): 11-16, 1992.

7.          Gľǰ|ľǨtspAľx8(3): 48-53, 1992.

8.          Chang, Y.S., Kuo, S.C., Weng, S.H., Jan, S.C., Ko, F.N. and Teng, C.M.: Inhibition of Platelet Aggregation by Shikonin Derivatives Isolated from Arnebia euchroma (Royle) Johnst. Planta Medica 59: 401-404, 1993.

9.          Shen, C.C. Chang, Y.S. and Ho, L.K. : Nuclear Magnetic Resonance Studies of 5,7-Dihydroxyflavonoids. Phytochemistry. 34: 834-845, 1993.

10.      Ho, L.K., Lin, C.C. and Chang, Y.S.: Investigation of Chemical Components from Scurrula liquidambaricolus (Hayata) Danser. J. Chin. Med. 4: 151-155, 1993.

11.      iwBtBBsnGOWժ´isI.¡X´ɤΰi򦨤QAعA~s24(3): 253-264, 1993.

12.      tBiwBBsnGOWժ´isII.ӭMaBiإߤΰi󤧱QAx5(3): 123-134, 1994.

13.      snBiwBtBGQβӭMaBiͲժ餤ĦImperatorin޳NAعAǷ|168: 32-48, 1994.

14.      ͡BBiҬ¡BءBiEGjaϤıШ|pլdsAШ|eUMDpesiA1994.

15.      Ho, L.K., Chang, C.R. and Chang, Y.S. : Chemical Components from Triumfetta bartramia. J. of Chin. Chem. Soc. 42: 93-95, 1995.

16.      Ko, F.N., Lee, Y.S., Kuo, S.C., Chang, Y.S. and Teng, C.M.: Inhibition on Platelet Activation by Shikonin Derivatives Isolated from Arnebia euchroma. Biochimica et Biophysica ACTA 1268: 329-334, 1995.

17.      iBaB©BGpwįΤ辯ΤҹAľǰ|x4(1): 67-78, 1995.

18.      BQaB©BۡBGӬksAľǰ|x4(2):107-113, 1995.

19.      LiBBsnGħŲws(1)--ϡBXjϻPhǩϤ배AعA~s44 (2): 101-103, 1995.

20.      צB\BiþBsnGJŲws(1)--JBJP˸J배AOW48(1):57-68, 1995.

21.      B©GxWĬs{pΥӵoiͶաAħ18(12): 637-640, 1995.

22.      Chang, Y.S., Lin, M.S., Jiang, R.L., Huang, S.C., and Ho, L.K.: 20-Epibryonolic Acid, Phytosterol and Ellagic Acid from Coriaria intermedia. Phytochemistry, 42(2): 559-560, 1996.

23.      Wu, C.R., Hsieh, M.T., Huang, S.C., Peng, W.H., Chang, Y.S. and Chen, C.F.: Effects of Gastrodia elata and its Active Constituents on Scopolamine-Induced Amnesia in Rats, Planta Medica, 62(4): 317-321, 1996.

24.      Lee V.J., Ho L.K., Hsieh M.T., Chang Y.S.* : Studies on the Constituents of the Roots of Celastrus punctatus, J. Chin. Med. 8(2): 95-101, 1997.

25.      ͬ¡B©BPʡBiB*GlSchizandrinGomisin AwqΧܨxlˤsAx8(3): 155-164, 1997.

26.      *BɹaBۡB©BtGOWħIJzǬsAx8(3): 165-176, 1997.

27.      BҷB§GhsAx8(3): 177-187 ,1997.

28.      Chan S.C., Chang, Y.S., Kuo, S.C. : Neoflavonoids from Dalbergia odorifera, Phytochemistry 46(5): 947-949, 1997.

29.      Lee V.J., Chang Y.S.., Hsieh M.T., Ho L.K: Antitumor and Antioxidant Effect of Celastrol Isolated from Celastrus punctatus, Chin Med Coll J 6(3): 203-210, 1997.

30.      ӵoB¤B©BB~áGӾ|հa۵MO@ϵ}MĥδӪլdAľǰ|x6(3): 227-234, 1997.

31.      Chan, S.C., Chang Y.S., Wang J.P., Chen S.C., Kuo S.C.: Three New Flavonoids and Antiallergic, Anti-inflammatory Constituents from the Heartwood of Dalbergia odorifera, Planta Medica 64(2): 153-158, 1998.

32.      Young Hae Choi, Jung Yeon Kim, Jung Hwan Ryu, Ki-Pung Yoo, Yuan Shiun Chang and Jinwoong Kim: Supercritical Carbon Dioxide Extraction of Podophyllotoxin from Dysosma pleuantha Roots, Planta Medica, 64(2): 482-483,1998.

33.      G괭BLLBPwB_BBʭסGNɫ̭勵`HզyX´iBկ-4~礧sAxWǬx3(3): 166-173, 1998.

34.      G괭BLLBPwBʭסBB_Gɫ̭PʯϹPGֲy񶡥կ-4Τʥզy´isAľǰ|x7(3): 1-9, 1998.

35.      µۡBBʻB§B©B*Għ[ukPǤ辯tqܤƤQAx9(3): 145-155, 1998.

36.      Yoe-Ray Ku, Kuo-Ching Wen, Li-Kang Ho and Yuan-Shiun Chang*: Determination of Xanthine Bronchodilators in Adulterated Chinese Herbal Preparations by High Performance Liquid Chromatography, J Chin Pharma, 50: 337-350, 1998.

37.      Hui-Ju Wang, Chun-Lin Chu, Yu-Ling Ho, Yuan-Shiun Chang, Chi-Sheng Jimmy Yang: Activation of Hippocampal Neurons by Ginseng Extract, Chin Med Coll J 7(4): 77-82, 1998.

38.      IB}ìFBABB¡B׽BBGTءGjnشMXLMtqwA_jǾdz30(6): 22-23, 1998.

39.      IB}ìFBABB¡B׽BBGTءGشMXLMtqwA_jǾdz30(6): 24, 28, 1998.

40.      Ӻ֡BɹaBiBۡB*GOW~ΡBVΤī~ؤլdAľǰ|x8(1): 35-46, 1999.

41.      Yoe-Ray Ku, Kuo-Ching Wen, Li-Kang Ho and Yuan-Shiun Chang: Solid-phase extraction for the determination of caffeine in traditional Chinese medicinal prescriptions containing Theae Folium by high performance liquid chromatography, J Pharm Biomed Anal 20:351-356, 1999.

42.      ׽BǬwB*GJjƩʼŦX֫ժ۱߷PV@αQAxWǬx4(2): 129-134, 1999.

43.      Yoe-Ray Ku, Kuo-Ching Wen, Li-Kang Ho and Yuan-Shiun Chang*: Solid-phase Extraction and High Performance Liquid Chromatography Determination of Steroids Adulterated in Traditional Chinese Medicines, Ī~R 7(2):123-130, 1999.

44.      Yoe-Ray Ku, Yuan-Shiun Chang*, Kuo-Ching Wen and Li-Kang Ho: Analysis and Confirmation of Synthetic Anorexics in Adulterated Traditional Chinese Medicines by High Performance Capillary Electrophoresis, Journal of Chromatography A 848:537-543, 1999.

45.      Ӻ֡BۡB*GOWjHͤڱHͤʵAľǰ|x8(3): 15-24, 1999.

46.      ͬ¡BdA͡B§B©BJpB*GpPͪPlͪRhʤAx10(4): 249-259, 1999.

47.      ֡BاӡB©BjBiB*BxfrzAx10(4): 261-268, 1999.

48.      _ΤB¤B~áBtB*GܻTħĥδӪǦҹAľǰ|x8(4): 7-14, 1999.

49.      ֡BاӡBBiBjB©Gvxe辯ܤHBxfr@ΤQAx11(1): 1-8, 2000.

50.      B家裡BB©Gѳ(Gastrodia eleta Bl.)ƾǦάʤsAĬx1(2):71-76, 2000.

51.      c١BLBtB*GOW^׳(Helicteres angustifolia Linnaeus)IJ´ǬsAĬx1(2):105-116, 2000.

52.      c١B~B§B*GOW^׳(Helicteres angustifolia Linnaeus)IJzʵAx11(3):143-151, 2000.

53.      c١BLBtB§B*GOWM˯(Ixeris laevigata var. oldhami)IJ´ǬsAĬx1(3):183-198, 2000.

54.      B家裡BB©Gѳ(Gastrodia elata Blume)~ŲwPtѳ¤Ĥ辯tqwAĬx1(3):199-210, 2000.

55.      Yuan-Shiun Chang, Yoe-Ray Ku, Kuo-Ching Wen and Li-Kang Ho: Analysis of Synthetic Gastrointestinal Drugs in Adulterated Traditional Chinese Medicines By HPCE, Journal of Liquid Chromatography & Related Technologies 23(13): 2009-2019, 2000.

56.      ͬ¡BB§GOW(Coriaria intermedia Matsum)ڤκؤlsAx11(2): 95-101, 2000.

57.      Kuo-Liang Lu, Yoe-Ray Ku, Kuo-Ching Wen, Li-Kang Ho and Yuan-Shiun Chang*: Analysis of Flavonoids and Coumarins in Ixeris laevigata var. oldhami By HPLC, Journal of Liquid Chromatography & Related Technologies, 23(16): 2573-2583, 2000.

58.      ײtBjB߯]B*GLss(Vernonia gratiosa Hance)Ѽh@ΤsAĬx1(4):283-291, 2000.

59.      Ji Suk Lee, Jinwoong Kim, Bo Yeon Kim, Hyun Sun Lee, Jong Seog Ahn and Yuan Shiun Chang*: Inhibition of Phospholipase Cg1 and Cancer Cell Proliferation by Triterpene Esters from Uncaria rhynchophylla, Journal of Nature Products, 63(6): 753-756, 2000.

60.      Kuo-Liang Lu, Yuan-Shiun Chang, Li-Kang Ho, Chun-Ching Lin and Chin-Chuan Tsai: The Evaluation of the Therapeutic Effect of Tao-Shang-Tsao a-Naphthylisothiocyanate and Cabon Tetrachloride-Induced Acute Liver Damage in Rats, American Journal of Chinese Medicine, 28(3-4): 361-370, 2000.

61.      MBɹaB§B*GŮڤtGf}GB-2-2-m-1, 4-f}Ax12(1):41-49, 2001.

62.      ײtBjBMB*GLss{۵oBʶqPĪoj˧@ΤvTAĬx2 (1): 11-17, 2001.

63.      ҷB~B§B*G(Ecdysanthera utilis Hayata)IJzʵAx12 (2): 109-117, 2001.

64.      ҷB⦰tB§B*Gt(Cyathula officinalis Kuan)sAx12 (3): 203-210, 2001.

65.      Yuan-Shiun Chang*, Yoe-Ray Ku, Jer-Huei Lin, Kuo-Liang Lu and Li-Kang Ho: Analysis of three lupane type triterpenoids in Helicteres angustifolia by high-performance liquid chromatography, Journal of Pharmaceutical and Biomedical Analysis, 26 (5-6): 849-855, 2001.

66.      ɹaBۡB*GQŤQɬhΧܵo@ΤsAĬx2 (4): 263-271, 2001.

67.      ɹaBLBMBtB*GOŮħŲOsAx 12 (4): 267-283, 2001.

68.      HB\²KB*GvħŦrzǬsAŦPzRx 13 (4): 195-201, 2001.

69.      Yuan Shiun Chang*, Yu Ling Ho: Studies on the Homonymic Chinese Crude Drug Species in Taiwan-Evaluation of the quality of Da-Ching-Yeh and Ching-Dai. Analytical Science, 17 (Supplement): a423-a426, 2001.

70.      HBUB*Gtq辯¹aĪIJGۼhRAĬx3 (1): 9-18, 2002.

71.      Kuo-Liang Lu, Chin-Chuan Tsai, Li-Kang Ho, Chun-Ching Lin and Yuan-Shiun Chang*: Preventive Effect of the Taiwan Folk Medicine Ixeris laevigata var. oldhami on a-Naphthylisothiocyanate and Cabon Tetrachloride Induced Acute Liver Injury in Rats, Phytotherapy Research, 16: S45-S50, 2002.

72.      Yuan-Shiun Chang*, Jeng-Shyan Deng, Yoe-Ray Ku: Determination of aristolochic acid in traditional Chinese medicinal prescriptions containing Radix Aristolochiae Fangchi by HPLC, Journal of Liquid Chromatography & Related Technologies, 25 (6): 961-975, 2002.

73.      Yu-Ling Ho, Yuan-Shiun Chang: Studies on the antinociceptive, anti-inflammatory and antipyretic effects of Isatis indigotica root. Phytomedicine 9: 419-424, 2002.

74.      Yoe-Ray Ku, Chi-Yuan Chen, Li-Kang Ho, Jer-Huei Lin and Yuan-Shiun Chang*: Analysis of Flavonoids in Vernonia paltula by high-performance liquid chromatography, Ī~R 10 (3): 139-142, 2002.

75.      Yuan-Shiun Chang, Eun-Kyoung Seo, Charlotte Gyllenhaal, Keith I. Block: Panax ginseng: a role in cancer therapy? Integrative Cancer Therapies 2(1): 13-33, 2003.

76.      Yu-Ling Ho, Kuo-Ching Kao, Huei-Yann Tsai, Fu-Yu Chueh and Yuan-Shiun Chang*: Evaluation of Antinociceptive, Anti-inflammatory and Antipyretic Effects of Strobilanthes cusia Leaf Extract in Male Mice and Rats. American Journal of Chinese Medicine 31: 61-69, 2003.

77.      Youn-Yuen Shu, Ming-Yu Ko and Yuan-Shiun Chang: Microwave-assisted extraction of ginsenosides from ginseng root. Microchemical Journal 74: 131-139, 2003.

78.      Kuo-Ching Kao, Yu-Ling Ho, Fu-Yu Chueh, Jih-Pyang Wang, Yuan-Shiun Chang*: Antipyretic, analgesic and anti-inflammatory activities of Strobilanthes formosanus. The Chinese Pharmaceutical Journal 55: 55-63, 2003.

79.      Kuo-Ching Kao, Yu-Ling Ho, I-Hsin Lin, Li-Kang Ho, Yuan-Shiun Chang*: Flavone Glycosides from Strobilanthes formosanus. Journal of the Chinese Chemical Society 51: 199-204, 2004.

80.      Yoe-Ray Ku, Yu-Ling Ho, Chi-Yuan Chen, Li-Kang Ho and Yuan-Shiun Chang*: Analysis of N-cis- and N-trans-feruloyl 3-methyldopamine in Achyranthes bidentata by HPLC. Journal of Liquid Chromatography & Related Technologies 27(4): 727-736, 2004.

81.      zDB@fBɹaBiBLyHB*GOWĩиg{pPxҽլdQAxWǬx10 (4): 204-211, 2005C

82.      J.C. Chen , T.Y. Ho, Y.S. Chang, S.L. Wu, , C.Y. Hsiang: Anti-diarrheal effect of Galla chinensis on the E. coli heat-labile enterotoxin and ganglioside interaction, J. Ethnopharmacol. 103: 385-391, 2006.

83.      Haw Yaw Young, Jung-Chun Liao, Yuan-Shiun Chang, Yen-Lin Luoa, Ming-Chin Lu, Wen-Huang Peng, Synergistic Effect of Ginger and Nifedipine on Human Platelet Aggregation: A Study in Hypertensive patients and Normal Volunteers, American Journal of Chinese Medicine. 34 (4): 545-551. 2006.

84.      zDB@fBBɹaBiBLyHB*GOWaϥĩЮO欰άvT]QAȺ޲zZ 7(3): 323-341, 2006C

85.      LqBءBBdBBsΡBnB綩BBŤGϪAʪլdPʦRAxWA~s55(3): 190-200, 2006C

86.      Susan Matthew, Kuo-Ching Kao, Yuan-Shiun Chang and Pedro Abreuy: Ellagic acid glycosides from Turpinia ternata. Natural Product Research, 21(1), 83-88, 2007.

87.      Guan-Jhong Huang, Ming-Jyh Sheu, Hsien-Jung Chen, Yuan-Shiun Chang, Yaw-Huei Lin: Growth Inhibition and Induction of Apoptosis in NB4 Promyelocytic Leukemia Cells by Trypsin Inhibitor from Sweet Potato Storage Roots. Journal of Agricultural and Food Chemistry. 55: 2548-2553, 2007.

88.      Guan-Jhong Huang, Hsien-Jung Chen, Yuan-Shiun Chang, Ming-Jyh Sheu, and Yaw-Huei Lin: Recombinant Sporamin and Its Synthesized Peptides with Antioxidant Activities in vitro. Botanical Studies. 48: 133-140, 2007.

89.      Guan-Jhong Huang, Ming-Jyh Sheu, Hsien-Jung Chen, Yuan-Shiun Chang, Yaw-Huei Lin: Inhibition of Reactive Nitrogen Species in Vitro and ex Vivo by Trypsin Inhibitor from Sweet Potato Tainong 57 Storage Roots. Journal of Agricultural and Food Chemistry. 55: 6000-6006, 2007.

90.      Heng-Yuan Chang, Wen-Huang Peng, Ming-Jyh Sheu, Guan-Jhong Huang, Zong-Chung Leu1, Mu-Chuan Tseng, Yu-Ling Ho, Yuan Shiun Chang*: Analgesic and Anti-inflammatory Activities of Phellinus merrillii, Mid-Taiwan Journal of Medicine 12(2): 76-82, 2007.

91.      Hsieh YC, Hsieh SJ, Chang YS, Hsueh CM, Hsu SL: The lipoxygenase inhibitor, baicalein, modulates cell adhesion and migration by up-regulation of integrins and vinculin in rat heart endothelial cells, British Journal of Pharmacology 151: 1235-1245, 2007.

92.      Chiou-Fung Chyu, Mei-Ru Ke, Yuan-Shiun Chang, and Yueh- Hsiung Kuo: New Cadinane-Type Sesquiterpenes from the Roots of Taiwania cryptomerioides Hayata. Helvetica Chimica Acta 90: 1514-1521, 2007.

93.      Heng-Yuan Chang, Wen-Huang Peng, Ming-Jyh Sheu, Guan-Jhong Huang, Mu-Chuan Tseng, Ming-Tsung Lai, Yu-Ling Ho and Yuan Shiun Chang*: Hepatoprotective and antioxidant effects of ethanol extract from Phellinus merrillii on carbon tetrachloride-induced liver damage, The American Journal of Chinese Medicine 35(5): 793-804, 2007.

94.      Jaw-Chyun Cheng, Yuan-Shiun Chang, Shih-Lu Wu, De-Cheng Chao, Chih-Shiang Chang, Chia-Cheng Li, Tin-Yun Ho, Chien-Yun Hsiang: Inhibition of Escherichia coli heat-labile enterotoxin-induced diarrhea by Chaenomeles speciosa, Journal of Ethnopharmacology 113(2): 233-239, 2007.

95.      Heng-Yuan Chang, Yu-Ling Ho, Ming-Jyh Sheu, Yaw-Huei Lin, Mu-Chuan Tseng, Sheng-Hua Wu, Guan-Jhong Huang and Yuan-Shiun Chang*: Antioxidants and free radical scavenging activity of Phellinus merrillii extracts, Botanical Studies 48: 407-417, 2007.

96.      Guan-Jhong Huang, Hsien-Jung Chen, Yuan-Shiun Chang, Te-Ling Lu, and Yaw-Huei LinGSweet potato storage root thioredoxin h2 with both dehydroascorbate reductase and monodehydroascorbate reductase activities. Botanical Studies 49 (1):1-7, 2008.

97.      Guan-Jhong Huang, Yu-Ling Ho, Hsien-Jung Chen, Yuan-Shiun Chang, Shyh-Shyun Huang, Hsin-Jung Hung, And Yaw-Huei Lin: Sweet potato storage root trypsin inhibitor and their peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activity in vitro. Botanical Studies 49: 101-108, 2008.

98.      Guan-Jhong Huang, Hsin-Chih Lai, Yuan-Shiun Chang, Te-Ling Lu, Ming-Jyh Sheu, H.Y Chang and Yaw-Huei Lin: Antimicrobial, dehydroascorbate reductase and monodehydroascorbate reductase activities of defensin from sweet potato (Ipomoea batatas [L.] Lam Tainong 57) storage roots. Journal of Agricultural and Food Chemistry 56: 2989- 2995, 2008.

99.      Hui-Ling Liao, Jin-Tang Chen, Tso-Chiang Ma, Yuan-Shiun Chang*: Analysis of Drug-Drug Interactions in Nursing Homes in Central Taiwan, Archives of Gerontology and Geriatrics 47: 99-107, 2008.

100.  Hui-Ling Liao, Tso-Chiang Ma, Yen-Lin Chiu, Jin-Tang Chen, Yuan-Shiun Chang*: Factors Influencing the Purchasing Behavior of TCM Outpatients in Taiwan, Journal of Alternative and Complementary Medicine 14(6): 741-748, 2008.

101.  Guan-Jhong Huang, Heng-Yuan Chang, Hsien-Jung Chen, Te-Ling Lu, Yuan-Shiun Chang, Ming-Jyh Sheu, and Yaw-Huei Lin: Effects of Trypsin inhibitor on Plasma Antioxidant Activity and Lipid levels in mice from sweet potato roots. Journal of the Science of Food and Agriculture 88: 2556-2562, 2008.

102.  Shyh-Shyun Huang, Guan-Jhong Huang, Yu-Ling Ho, Yaw-Huei Lin, Hsin-Jung Hung, Tien-Ning Chang, Man-Jau Chan, Jial-Jhen Chen, Yuan-Shiun Chang*: Antioxidant and antiproliferative activities of the four Hydrocotyle species from Taiwan: Botanical Studies 49: 311-322, 2008.

103.  Man-Jau Chang, Guan-Jhong Huang, Yu-Ling Ho, I-Hsin Lin, Shyh-Shyun Huang, Tien-Ning Chang, Heng-Yuan Chang and Yuan-Shiun Chang*: Study on the antioxidant activities of the crude extracts from the roots of Arnebia euchroma and Lithospermum erythrorhizon, Mid-Taiwan Journal of Medicine 13: 113-121, 2008.

104.  @lBɹaBiþGOW^IJ´ǬsAs;dz3: 19-38A2008C

105.  Guan-Jhong Huang, Ming-Jyh Sheu, Yuan-Shiun Chang, Te-Ling Lu, Heng-Yuan Chang, Shyh-Shyun Huang, Yaw-Huei Lin: Isolation and characterisation of invertase inhibitor from sweet potato storage roots. Journal of the Science of Food and Agriculture 88: 2615-2621, 2008.

106.  Shyh-Shyun Huang, Guan-Jhong Huang, Wen-Huang Peng, Yu-Ling Ho, Man-Jau Chang, Hsin-Jung Hung, Tien-Ning Chang and Yuan-Shiun Chang*: Analgesic and Anti-inflammatory Activities of an Aqueous Extract of Hydrocotyle batrachium Hance in Mice. Mid-Taiwan Journal of Medicine 13(4):179-185, 2008.

107.  Yu-Shiang Chou, Yu-Ling Ho, Chih-Wen Ding and Yuan-Shiun Chang*:  New Antioxidant Phenylethanol Glycosides from Torenia concolor. Journal of Asian Natural Products Research 11(2): 110-115, 2009.

108.  Jaw-Chyun Chen, Tin-Yun Ho, Yuan Shiun Chang, Shih-Lu Wu, Chia-Cheng Li, Chien-Yun Hsiang: Identification of E. coli enterotoxin inhibitors from traditional medical herbs by in silico, in vitro, and in vivo analyses. Journal of Ethnopharmacology 121(3):372-378, 2009.

109.  Guan-Jhong Huang, Shyh-Shyun Huang, Hsien-Jung Chen, Yuan-Shiun Chang, Shu-Jen Chang, Heng-Yuan Chang, Po-Chow Hsieha, Man-Jau Chang, Ying-Chin Lin: Cloning and expression of aspartic proteinase cDNA from sweet potato storage roots, Botanical Studies, 50:149-158,2009.

110.  Shang-Chih Lai, Wen-Huang Peng, Shun-Chueh Huang, Yu-Ling Ho, Tai-Hung Huang, Zhen-Rung Lai and Yuan-Shiun Chang*: Analgesic and Anti-inflammatory Activity of Methanol Extract from Desmodium triflorum DC in Mice. The American Journal of Chinese Medicine 37(3): 573-588, 2009.

111.  Tien-Ning Chang, Guan-Jhong Huang , Yu-Lin Ho,  Shyh-Shyun Huang, Heng-Yuan Chang and Yuan-Shiun Chang *: Antioxidant and antiproliferative activities of Crossostephium chinensis (L.) Makino. The American Journal of Chinese Medicine, 37(4): 797-814, 2009.

112.  Chia-Yang Li, Chi-Shiun Chiang, Min-Lung Tsai, Ruey-Shyang Hseu, Wun-Yi Shu, Chun-Yu Chuang, Yuh-Chang Sun, Yuan Shiun Chang, Jaung-Geng Lin, Chih-Sheng Chen, Ching-Lung Huang, Ian C. Hsu: Two-sided effect of Cordyceps sinensis on dendritic cells in different physioligical stages. Journal of Leukocyte Biology, 85(6): 978-986, 2009

113.  Heng-Yuan Chang, Ming-Jyh Sheu, Chun-Hung Yang, Zong-Chung Leu, Yuan Shiun Chang, Wen-Huang Peng, Shyh-Shyun Huang, Huang Guan-jhong: Analgesic effects and the mechanisms of anti-inflammation of hispolon in mice. Evidence-based Complementary and Alternative Medicine, doi:10.1093, 2009.